Published: 26 Jun 2026 1,284 views
A PhD scholarship is available within Professor Robert Edwards’ ARC Laureate Fellowship program, “New Horizons for Synthetic Phages”, at Flinders University.
Many bacteria contain dormant phages, known as prophages, hidden within their genomes. These phages can respond to environmental signals and switch from a dormant state to active replication, killing their bacterial hosts. However, we know very little about the signals that most phages detect, the proteins that sense those signals, or how these regulatory systems could be used to control synthetic phages.
This PhD project will investigate how microbial communities and bacterial isolates respond to chemical signals that induce phage activation. The candidate will use high-throughput assays, flow cytometry, anaerobic culturing, phage induction experiments, DNA sequencing, and metagenomics to identify compounds that activate prophages. Candidate signals may include antibiotics, microbial metabolites, oxidative stress compounds, short-chain fatty acids, polyphenols, and drug-like chemical scaffolds.
The project will also link experimental phage-induction data with genomic and metagenomic analyses to identify which phages respond to specific compounds and which phage-encoded proteins may detect those signals. These discoveries will help establish new ways to control phage behaviour, including the future design of synthetic phages that respond to defined environmental cues.
| Application Deadline | 01 Sep 2026 |
| Country to study | Australia |
| School to study | Flinders University |
| Type | PhD |
| Sponsor | Flinders University |
| Gender | Men and Women |
The scholarship includes:
To be eligible, applicants must:
All PhD projects are full-time. No positions are remote-only. Candidates must be physically based at Flinders University to ensure a strong, collaborative cohort is developed across the Laureate Fellowship program. Candidates will be expected to participate actively in laboratory meetings, cohort activities, research training, workshops, and relevant national or international conferences.
Interested applicants should submit:
Please direct expressions of interest to [email protected]
For more information, kindly visit Flinders University scholarship webpage.