RMIT University 2023 Bioinformatics Analysis of Tertiary Phase Glia in Preterm Brain Injury

This project will apply biostatistical analysis to RNAseq data to undercover novel roles for microglia and astrocytes in brain injury occurring in preterm born infants.

Permanent brain injury in babies can result from exposure to an inflammatory insult combined with being born preterm (<37 of 40 weeks’ gestation). Over their lifetime, these infants frequently struggle in academic and social settings due to cognitive and social deficits linked to their brain injuries. It is known that the cellular reactivity, termed the tertiary phase of injury persists into childhood and adolescence after early brain injury and is also observed after multiple other forms of brain injury. These changes involve dysfunction of astrocytes and microglia and they sensitise the brain to further injury. By identifying these changes creates opportunities for novel therapeutic development. This project will add to this field of research by identifying the signature of injury in a mouse model of preterm inflammatory brain injury.

• Table of Content
• About RMIT University
• Bioinformatics Analysis of Tertiary Phase Glia in Preterm Brain Injury
• Aim and Benefits of Bioinformatics Analysis of Tertiary Phase Glia in Preterm Brain Injury
• Requirements for Bioinformatics Analysis of Tertiary Phase Glia in Preterm Brain Injury Qualification
• Application Deadline
• How to Apply

About RMIT University

RMIT University (officially Royal Melbourne Institute of Technology, informally RMIT) is an Australian public research university based in Melbourne, Victoria. Founded in 1887 as the Working Men's College of Melbourne by Francis Ormond, it initially opened as a private night school offering instruction in art, science and technology in response to the industrial revolution in Australia. It was made a public university by act of the Parliament of Victoria in 1992 after merging with the Phillip Institute of Technology. A dual sector institute, its enrolment of 320 trades students in 1887 ... continue reading

Bioinformatics Analysis of Tertiary Phase Glia in Preterm Brain Injury

Aim and Benefits of Bioinformatics Analysis of Tertiary Phase Glia in Preterm Brain Injury

Project attached to a NHMRC funded grant, normal RMIT PhD Scholarship terms and conditions.

Requirements for Bioinformatics Analysis of Tertiary Phase Glia in Preterm Brain Injury Qualification

Standard RMIT conditions including English requirements, and either a Honours degree with a H1 grade,  or equivalent industry or academic experience. Please get in touch to discuss.

Application Deadline

How to Apply

Please email [email protected] to discuss the project.

For more details, visit RMIT University website.