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Lex:lead was founded in 2010 to continue the work of the Global Challenge, a group that had formed in 2001 under the International Bar Association to bring lawyers worldwide to the issue of development focusing on the least developed countries. Joining the Global Challenge in 2005, Anne was named its director. In 2010 the founding members set up Lex:lead as a New York Not-for-Profit registered charity with US Section 501(c)(3) tax exempt status.