The University of Pisa (Italian: Università di Pisa, UniPi) is an Italian public research university located in Pisa, Italy. It was founded in 1343 by an edict of Pope Clement VI. It is the 19th oldest extant university in the world and the 10th oldest in Italy. The prestigious university is ranked within the top 10 nationally and the top 400 in the world according to the ARWU and the QS. It houses the Orto botanico di Pisa, Europe's oldest academic botanical garden, which was founded in 1544.